Evidence-Based Longevity Science
Evidence-Based Longevity & Healthy Aging
Science-backed protocols for extending lifespan and healthspan through proven interventions
Your Complete Longevity Resource
Explore evidence-based interventions backed by scientific research
HMGB1 Biology
Understanding the master regulator of aging and how it transmits senescence systemically.
Diet & Nutrition
Mediterranean diet, green tea, berries, and omega-3s for HMGB1 reduction.
Exercise & Fitness
Resistance and aerobic training protocols for 20-50% mortality reduction and cognitive health.
Lifestyle Interventions
Caloric restriction, fasting protocols, and stress management for longevity.
Natural Compounds
EGCG, quercetin, curcumin, resveratrol, and ginsenosides with proven benefits.
Pharmaceutical Options
Metformin, glycyrrhizin, and emerging therapies for HMGB1 modulation.
Daily Protocols
Practical, evidence-based routines you can implement today.
Featured Guides & Popular Topics
Start with our most popular evidence-based guides
PriorityPopular
Brain Fog Solutions
Evidence-based strategies to clear mental fog and improve cognitive function naturally.
PriorityPopular
Break Weight Loss Plateau
12 science-backed strategies to restart fat loss when progress stalls.
Essential
Heart Disease Prevention
Comprehensive protocol to reduce cardiovascular risk through diet, exercise, and lifestyle.
New
Women's Strength Training
Science-backed guide debunking myths. 7.4x safer, 30% cardiovascular mortality reduction.
Research-backed
Exercise for Longevity
Optimal exercise protocols for 20-50% mortality reduction and cognitive health.
Essential
Visceral Fat Guide
Reduce dangerous abdominal fat linked to disease and mortality.
Priority
Mediterranean Diet Guide
Complete evidence-based guide to the diet with strongest longevity research.
Essential
Sleep Hygiene
23 evidence-based protocols to improve sleep quality and add years to your life.
Popular
Intermittent Fasting Guide
Complete guide to IF protocols from 16:8 to OMAD with metabolic benefits.
Disease Prevention Protocols
Evidence-based strategies to prevent the leading causes of death
Heart Disease
Leading cause of death. Learn evidence-based prevention strategies.
#1 Cause of Death
Cancer
Comprehensive prevention protocols backed by research.
Critical Prevention
Type 2 Diabetes
Prevent and reverse metabolic dysfunction naturally.
Reversible
Visceral Fat
Reduce dangerous abdominal fat linked to disease and mortality.
High Impact
All Diseases
Complete guide to preventing leading causes of death.
Essential reading
Free Health Tools
Interactive calculators to assess your health and track progress
BMI Calculator
Calculate your Body Mass Index and assess your diabetes risk with weight loss targets.
Calculate NowCalorie Calculator
Calculate daily calorie needs for weight loss, maintenance, or muscle gain.
Calculate NowTDEE Calculator
Calculate your Total Daily Energy Expenditure based on activity level.
Calculate NowMacro Calculator
Calculate optimal protein, carbs, and fat for your goals.
Calculate NowBiological Age Calculator
Estimate your biological age based on health markers and lifestyle factors.
Calculate NowBody Fat Calculator
Calculate your body fat percentage and understand your body composition.
Calculate Now8+ Years
Added Life Expectancy
with optimal lifestyle habits
40%
Lower Disease Risk
following evidence-based protocols
30 Min
Daily Exercise
can reduce mortality significantly
Simple
Science-Backed Habits
anyone can start today
Frequently Asked Questions
Quick answers to common longevity questions
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Track Your Longevity Journey
Build science-backed habits, track your progress, and earn Longevity Points. Start free today.